Description
“Sodic / Sodic DS” is Sodium bicarbonate tablets which is used as an alkalinizing agent in the treatment of metabolic acidosis. Sodium bicarbonate also may be used as an alkalinizing agent in advanced cardiovascular life support (ACLS) during cardiopulmonary resuscitation (CPR) and in the treatment of certain intoxications (e.g., methyl alcohol, phenobarbital, salicylates) to decrease renal reabsorption of the drug or to correct acidosis.
Sodium bicarbonate also is used to increase urinary pH in order to increase the solubility of certain weak acids (e.g., cystine, sulfonamides, uric acid) or in the treatment of hemolytic reactions requiring alkalinization of the urine to diminish the nephrotoxic effects of blood pigments. In addition, the drug is used in the treatment of severe diarrhea accompanied by substantial GI bicarbonate loss and as an adjunct in the treatment of hyperkalemia to induce the cellular uptake of potassium and return the ratio of intracellular to extra cellular potassium concentration toward normal.
Each film-coated tablet of Sodic contains Sodium Bicarbonate USP 500 mg
Each film-coated tablet of Sodic-DS contains Sodium Bicarbonate USP 1000 mg
Some of the side effects although may occur rarely with Sodium Bicarbonate (Sodic) are nausea or vomiting, headache, muscle pain, swelling of feet, ankles or legs, decreased appetite, unusual tiredness, constipation, dry mouth or increased thirst or increased urination.
Some of the common adverse reactions which may occur with Sodium Bicarbonate (Sodic Exacerbation of CHF. Rebound hyperacidity, milk-alkali syndrome, Hypernatremia, alkalosis, Extravasation with cellulitis, tissue necrosis, ulceration, venous irritation, tetany or edema.
Sodium Bicarbonate should not be used if you have certain medical conditions. Before using this product, consult your doctor if you have: a certain breathing problem (pulmonary edema), congestive heart failure, severe kidney disease (e.g., inability to make urine), severe liver disease (e.g., ascites, cirrhosis), high sodium levels, and swollen ankles/legs/feet due to retaining water (peripheral edema). If you have any of the following health problems, consult your doctor before using Sodium Bicarbonate: low calcium levels, high blood pressure, heart problems (e.g., irregular heartbeat), and kidney disease.
Because this medication contains salt (sodium), do not use if you are on a salt-restricted diet. During pregnancy, this medication should be used only when clearly needed. This medication may worsen high blood pressure during pregnancy (toxemia of pregnancy). Discuss the risks and benefits with your doctor.
Sodium Bicarbonate (Sodic) therapy increases plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and reverses the clinical manifestations of acidosis. Plasma concentration is regulated by the kidney through acidification of the urine when there is a deficit or by alkalinization of the urine when there is an excess. Bicarbonate anion is considered “labile” since at a proper concentration of hydrogen ion (H+) it may be converted to carbonic acid (H2CO3) and thence to its volatile form, carbon dioxide (CO2) excreted by the lung. Normally a ratio of 1:20 (carbonic acid; bicarbonate) is present in the extra cellular fluid. In a healthy adult with normal kidney function, practically all the glomerular filtered bicarbonate ion is reabsorbed; less than 1% is excreted in the urine